Discovery of potential cyclooxygenase inhibitors using in silico docking studies
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چکیده
منابع مشابه
In Silico Screening Studies on Methanesulfonamide Derivatives as Dual Hsp27 and Tubulin Inhibitors Using QSAR and Molecular Docking
The expression of heat shock protein 27 (Hsp27) as a chaperone protein, is increased in response to various stress stimuli such as anticancer chemotherapy. This phenomenon can lead to survive of the cells and causes drug resistance. In this study, a series of methanesulfonamide derivatives as dual Hsp27 and tubulin inhibitors in the treatment of cancer were applied to quantitative structure–act...
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ژورنال
عنوان ژورنال: Bangladesh Journal of Pharmacology
سال: 2012
ISSN: 1991-0088,1991-007X
DOI: 10.3329/bjp.v7i1.10007